Transport phenomena and structure formation at the micro/nanometer scale in biomedicine and materials science
Partners (6): UVT-Physics (leader), IeAT, etc
Transport phenomena and structure formation play an important role in nature. The development of micro/nanotechnologies calls for new physical models and simulation codes, which are able to describe the processes at this scale both in biomedical sciences and in material science and technology. The fact that the physical investigation methods of transport and structure formation are the same in these domains, lead us to the idea of building a consortium of experts in these fields (West University of Timisoara, Romanian Academy – Timisoara Division and Victor Babes University of Medicine and Pharmacy Timisoara, Babes-Bolyai University Cluj-Napoca, E-Austria Institute). In order to validate the models by comparison with experimental results, two new partners have been included (National Institute for Research and Development for Izotopic and Molecular Technologies Cluj-Napoca and University of Medicine and Pharmacy „Carol Davila” Bucharest); these will perform experiments on the self-assembly of biological cells into living tissues. The aims of the project are: 1. to develop a common platform for the simulation of transport phenomena and structure formation at the micro-/nanometer scale in material and biomedical sciences, starting from the platform that exists at West University of Timisoara and using the infrastructure and expertise of the partner institutions. 2. to develop new models: Monte Carlo simulations of structure formation in living tissues; Lattice Boltzmann moldes for simulating cell migration in tissue engineering, models for transport phenomena through the ionic channels from biological cell membranes, Lattice-Boltzmann models for designing micro-eloctro-mechanics (MEMS) channels and studying mesoscopic flows therein; Phase Field models for crystallization phenomena and grid-independent models for thermal stress in crystals. Furthermore, the infrastructure needed to implement and efficiently exploit these models in the framework of efficient computer codes (grid generation, visualization and user friendly interface). Aiming to enchance performances, the computer codes will be optimized to run on GRID networks, benefitting from the advantages of parallel computing along with the inherent portability, thereby facilitating cooperations with European partners. 3. to study the aggregation of biological cells and the growth of ionic crystals both experimentally and numerically, thereby optimizing the experiments and validating physical models and simulation techniques. 4. to contribute to the development of a new generation of specialists, anticipating that, in the following years, these phenomena will be of a major interest for companies working in the field of nanotechnologies.
For more information, please visit the NanoSim project site.